In 2006, the 4.6-liter Toyota 1UR-FE engine was released as a powertrain for SUVs, full-size pickups, and executive models intended for emerging markets. The power system is where it differs most from 1UR-FSE: distributed injection rather than direct.

The engines in the UR family are 1URFE, 1URFSE, 2URGSE, 2URFSE, and 3URFE.
The engine was mounted on:
- Toyota Land Cruiser J200 since 2012;
- Toyota Sequoia XK60 in 2010 – 2012;
- Toyota Tundra XK50 since 2010;
- Lexus GS 460 S190 in 2007 – 2011;
- Lexus GX 460 J150 since 2009;
- Lexus LS 460 XF40 in 2006 – 2017.
Specifications
| Production years | since 2006 |
| Displacement, cc | 4608 |
| Fuel system | MPI |
| Power output, hp | 296 – 347 |
| Torque output, Nm | 439 – 460 |
| Cylinder block | aluminum V8 |
| Block head | aluminum 32v |
| Cylinder bore, mm | 94 |
| Piston stroke, mm | 83 |
| Compression ratio | 10.2 |
| Features | ACIS and ETCS-i |
| Hydraulic lifters | yes |
| Timing drive | chain |
| Phase regulator | Dual VVT-i |
| Turbocharging | no |
| Recommended engine oil | 5W-30 |
| Engine oil capacity, liter | 8.6 |
| Fuel type | petrol |
| Euro standards | EURO 3/4 |
| Fuel consumption, L/100 km (for Lexus GX460 2009) — city — highway — combined |
17.7 9.9 12.8 |
| Engine lifespan, km | ~450 000 |
| Weight, kg | 216 |
Disadvantages of the 1UR-FE engine
Oil consumption is moderate for some owners;
The timing chain may abruptly loosen as a result of a hydraulic tensioner failure; the water pump begins to leak on runs up to 100,000 kilometers;
The ETCS-i electronic throttle system occasionally malfunctions; piston rings are a result of urban operation; there was an official recall in 2010 to replace the valve springs;
This powertrain’s overall dependability is significantly higher than average.
